Canine epilepsy is the most frequent neurological disease in canine medicine: it affects 5% of the global population and more than 20% of the dogs in some breeds.
This disease is characterized by the recurrence of seizures and can severely compromise the dog’s quality of life. Seizures can also be very scary for the dog’s owner.
Because of the considerable amount of epileptic dogs in some breeds, it is highly probable that epilepsy is an inherited disorder. It has already be proven for some breeds. In that case, the first seizure usually occurs in dogs between the ages of 6 months and 6 years. The type and intensity of seizures, the average start of the disease and the mode of transmission depend on the breed and they are very similar within a same breed.
Vetagro-Sup (Dr Catherine Escriou), the CNRS (Dr Catherine André and Pascale Quignon) and Antagene (Dr Anne Thomas) are currently working together on a project aiming to characterize the type of seizures which occurs in molosser breeds such as Dogue de Bordeaux, Cane Corso and Dogo Argentino. An inherited cause of epilepsy is highly probable in these breeds. They are suspected to have generalized and very intense seizures, occurring several times a day and poor response to antiepileptic drugs. We also hope to find the genetic cause of this epilepsy and to develop a screening test which could help to reduce the amount of epileptic dogs in these breeds.
In order to complete this project, we are looking for blood samples from epileptic Dogues de Bordeaux and their family (brothers, sisters, parents, litters….) and from non-epileptic Dogues de Bordeaux. You can help us by sending a blood sample from your dog (epileptic or non-epileptic) and joining a copy of his pedigree, along with the questionnaire provided by us. We ensure the total confidentiality of any information you can give us.
After collection the samples can be kept at 4°C and must be sent as soon as possible by mail at room temperature, avoiding week end and public holidays.
For any further information, you can contact us at : firstname.lastname@example.org